Viraxall LPT: White Paper

Viraxall LPT ™ White Paper

This material is provided for educational and informational purposes only to licensed health care professionals. This information is obtained from sources believed to be reliable, but its accuracy cannot be guaranteed. Herbs and other natural substances are very powerful and can occasionally cause dangerous allergic reactions in a small percentage of the population. Licensed health care professionals should rely on sound professional judgment when recommending herbs and natural medicines to specific individuals. Individual use of herbs and natural medicines should be supervised by an appropriate health care professional. The use of any specific product should always be in accordance with the manufacturer’s directions.

Viraxall (EGCG 98% LPT™) Uses:

Viraxall is formulated as a superior immune supportive supplement but has other activities including:

• Ultimate antioxidant support
• Anti-aging support
• Metabolic supportive – weight management

Dosage:

• Teavigo^©– 21 mg per LPT™
• Chew and swallow 1-2 tablets daily
• If Active Virus chew and swallow 4-6 tablets daily

Background:

Viraxall LPT™ as Teavigo^© is a unique, highly bioavailable, chewable liposomal tablet (lipotab LPT) using the polyphenol EGCG (epigallocatechin-3-gallate) from Green tea leaves (Camellia sinensis).  Viraxall LPT™ is used to support immunity.

EGCG from Green tea (Camellia sinensis) leaves

• EGCG (epigallocatechin-3-gallate) is the most abundant polyphenol catechin found in green tea leaves.
• Immune modulating – EGCG is reported in studies to have a dramatic effect on T cell functions, including T cell activation, proliferation, differentiation, and production of cytokines.[1] In particular, dysregulated T cell function with respect to different subsets of CD4(+) T cells is a critical pathogenic factor in the development of autoimmune inflammatory diseases.[2]
• Antiviral – reported to have antiviral effects and potential for COVID-19 supportive therapy[3]; reported to inhibit spike binding to ACE2 receptor in SARS-CoV-2 virus.[4]
• Antioxidant and prooxidant – prooxidant effects produce weight loss benefits. EGCG helps support a healthy GUT microbiome. EGCG was reported to decrease the growth of Fimicutes (reported increased in Insulin resistance and obesity) and increased growth of Akkermansia (reported important in lipid metabolism and weight management).[5] This also helps support improved immunity.
• Accumulation of senescent cells in adipose tissue plays an important role in obesity and age-related diseases. SIRT3, located in the mitochondria, can regulate ROS via different pathways. Using EGCG to target SIRT3 activating compounds may delay senescence of cells and senescence induced inflammatory processes.[6]
• Neuroprotective – antioxidant, anti-inflammatory for microglia; improves adult neurogenesis in the hippocampus.
• Antibacterial – interferes with the adsorption on host cells, inhibiting virus replication and reducing bacterial biofilm formation and toxin release.

• EGCG and Weight Management
  

Toxicity, Contraindications, or Side Effects: 

• There is no known toxicity or side effects from taking ingredients found in EGCG LPT, AT RECOMMENDED DOSAGES.
• DO NOT TAKE if you are allergic to any ingredient in EGCG LPT.
• EGCG is reported in animal studies to interact with several pharmaceuticals, although issues in humans are not reported. Patients should be carefully monitored if using EGCG and taking narrow therapeutic drugs, including digoxin, aminophylline, warfarin, quinidine and others.
• There is a study of 10 people drinking green tea and taking nadolol (Corgard).[7] Ten healthy volunteers received a single oral dose of 30 mg nadolol with green tea or water after repeated consumption of green tea (700 ml/day) or water for 14 days. Green tea markedly decreased the maximum plasma concentration (C(max)) and area under the plasma concentration-time curve (AUC(0-48)) of nadolol by 85.3% and 85.0%, respectively (P < 0.01), without altering renal clearance of nadolol. The effects of nadolol on systolic blood pressure were significantly reduced by green tea. It is to note that the green tea product used in this study was a special extract from Japan and exceptionally high in catechins (154mg/dl, or 2-5 x higher than normal green tea beverages).

Why Lipotabs?

The revolutionary Liposomal LPT^™ chewable tabs provide a safe and more efficient way for the body to absorb nutrients, peptides and other targeted therapeutic compounds. LPT does not have stability problems that plague the liposomal industry – LPT are proven stable.

Liquid liposomal products have inherent stability issues. Issues with Liquid Liposomes on the Market include:

• Needs significant heat to produce – makes product unstable and decomposes active and inert ingredients in the product
• Particles clump together to form larger and larger particle size
  • Liquid liposomes reported to grow from 100nm size to 3000nm over a 30-day period[8]
  • Larger particle size means less bioavailable
  • Larger size also means increased potential for side-effects

 LPT^™  particles don’t require heat for production and don’t “clump” like liquid liposomes over time.

• Means Greater Bioavailability
• Greater Stability
• Superior Product
• Superior Results
• No toxic excipients

Copyright © 2023 James B. LaValle, Natural Formulations All rights reserved.

No part of this material may be used or reproduced in any manner whatsoever, stored in a retrieval system, or transmitted in any form, or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission of the author.

This material is provided for educational and informational purposes only to licensed health care professionals. This information is obtained from sources believed to be reliable, but its accuracy cannot be guaranteed. Herbs and other natural substances are very powerful and can occasionally cause dangerous allergic reactions in a small percentage of the population. Licensed health care professionals should rely on sound professional judgment when recommending herbs and natural medicines to specific individuals. Individual use of herbs and natural medicines should be supervised by an appropriate health care professional. The use of any specific product should always be in accordance with the manufacturer’s directions.

[1] Pae M, Wu D. Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications. Food Funct. 2013;4(9):1287-303.

[2] Carmen P, et al. Induction of regulatory T cells by green tea polyphenol EGCG. Immunology Letters, 2011.139(1-2):7-13.

[3] Wang YQ, et al. Antiviral effects of green tea EGCG and its potential application against COVID-19. Molecules. 2021;26(13):3962.

[4] Liu J, et al. Epigallocatechin gallate from green tea effectively blocks infection of SARS-CoV-2 and new variants by inhibiting spike binding to ACE2 receptor. Cell Biosci. 2021;11(1):168.

[5] Perez-Burillo S, et al. Green tea and its relation to human gut microbiome. Molecules. 2021;26(13):3907.

[6] Lilja S, et al. Epigallocatechin Gallate Effectively Affects Senescence and Anti-SASP via SIRT3 in 3T3-L1 Preadipocytes in Comparison with Other Bioactive Substances. Oxid Med Cell Longev. 2020;2020:4793125.

[7] Misaka S, et al. Green tea ingestion greatly reduces plasma concentrations of nadolol in healthy subjects. Clin Pharmacol Ther. 20145;95(4):432-8.

[8] Lombardo D, Kiselev MA. Methods of Liposomes Preparation: Formation and Control Factors of Versatile Nanocarriers for Biomedical and Nanomedicine Application. Pharmaceutics. 2022;14(3):543.